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Supplement Guide

Magnesium Glycinate

The most bioavailable form of magnesium — and the one most likely to actually improve your sleep, reduce anxiety, and support muscle recovery.

Strong Evidence Sleep Recovery Check Interactions
Daily Dose
300–400mg
Elemental magnesium
Best Form
Glycinate
Highest absorption
When to Take
Before bed
30–60 min
Time to Work
1–2 weeks
Sleep improvement
Bioavailability
~80%
vs 4% for oxide
Monthly Cost
€12–25
Good value
What is it

What is Magnesium Glycinate?

Magnesium glycinate is magnesium bound to glycine, an amino acid. This binding dramatically improves absorption compared to cheaper forms like oxide or carbonate — and the glycine itself has independent calming and sleep-promoting effects.

Magnesium is involved in over 300 enzymatic processes in the body. Up to 75% of people in western countries don't get enough from diet alone — making it one of the most common and impactful deficiencies to address through supplementation.

Benefits

What the Research Shows

Who Needs It

Is Magnesium Glycinate Right for You?

✓ Take it if you...
  • Have trouble falling asleep or staying in deep sleep
  • Experience high stress or anxiety
  • Train regularly and want faster muscle recovery
  • Eat a typical western diet with little leafy greens, nuts or seeds
  • Experience muscle cramps, especially at night
  • Suffer from frequent headaches or migraines
⚠ Consider carefully if you...
  • Have kidney disease — consult your doctor first
  • Take antibiotics or certain blood pressure medications
  • Already take a multivitamin with high magnesium content
Dosing Protocol

How to Take Magnesium Glycinate

Standard Protocol Most people
300–400mg
Take 30–60 minutes before bed. This is elemental magnesium — check your label as glycinate capsules are heavier. A 500mg glycinate capsule typically contains ~70mg elemental magnesium.
💡 Important

Check elemental magnesium on the label, not total capsule weight. "500mg magnesium glycinate" ≠ 500mg of magnesium. Most people need 4–6 capsules to reach 300mg elemental magnesium.

Interactions

What NOT to Take With Magnesium

Zinc and Iron — both compete for the same absorption pathways. Take magnesium at least 2 hours apart from zinc or iron supplements.

Calcium — high-dose calcium can reduce magnesium absorption. Take them at separate times if both are above 500mg.

Vitamin D — a positive interaction. Magnesium is required to activate vitamin D. If you take D3, adequate magnesium makes it significantly more effective.

Antibiotics — some antibiotics bind to magnesium and reduce absorption of both. Space them by at least 2 hours.

Recommended Products

What to Buy

Thorne Magnesium Bisglycinate
Premium third-party tested, clean label, highly trusted
Best quality
NOW Foods Magnesium Glycinate
GMP certified, good elemental magnesium content, affordable
Best value
Doctor's Best High Absorption Magnesium
TRAACS chelated form, widely available across Europe
Most popular
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